Note: The talents listed are what I think work best when fighting each champion.

Androxus: Who has the better aim competition. | Talent: Any

Bombking: Easily zonable and pretty big hitbox. | Talent: Cursed Revolver

Cassie: Getting the jump on her usually secures the kill. | Talent Any

Corvus: Without projection, he is an easy kill. | Talent: Any

Dredge: Keep your distance. If he uses a shortcut, disengage as he'll bait you into CQB. | Talent: Any

Drogoz: Easy target. Use your air mobility to make it harder for him to hit you. | Talent: Cursed Revolver

Evie: If you have good tracking and awareness, Evie shouldn't be hard to take down. Make mental notes of where she used her blink if running wormhole. Expect iceblock baits. Use air mobility. Going against Evie (especially a good one) takes practice and patience. | Talent: Cursed Revolver

Furia: Without wings of wrath and pyre strike, she is an easy kill. Be wary of CQB as they permit a high chance of being stunned. | Talent: Any

Io: Without lunar leap, she is an easy kill, though be cautious when Luna is nearby as some Io's use Luna as a shield or to stun. | Talent: Any

Kinessa: Without a teleporter, she is an easy kill. Watch out for mines. Use flanking to your advantage. Avoid attacking from the front. | Talent: Any

Koga: Waste his energy. Make sure to use your dashes conservatively as some Koga's use their ult as a last resort. Andro's TTK is higher than Koga's. Use that as an advantage. | Talent: Any

Lex: Another who has better aim competition. Use caution if Lex is running Discovery as you'll be melted if you're his target. (Trust me, I know) | Talent: Any

Maeve: Just like Evie. Tracking and awareness are key. | Talent: Any

Mal'Damba: Be wary of stuns. A good Damba can shut you down. | Talent: Any

Moji: Bait out her Magic Barrier and keep your distance. | Talent: Cursed Revolver

Seris: Poke and bait out her Shadow Travel. She's an easy kill afterward. Be wary of Agony or Soul Collector Seris's as they can shut you down if you're not careful. | Talent: Any

Skye: Buy illuminate. Andro's TTK is higher than Skye's. | Talent: Any

Tiberius: Quick burst damage is key. Save your reversal for his combat stance and use air mobility. Tiberius has pretty good zoning abilities so shutting him down quickly is the best option. | Talent: Any

Tyra: Quick burst damage is key. Shut her down before she kills you. Be wary of burn monster as you become a literal sitting duck. | Talent: Any

Viktor: CQB is key. Range is what screws you over. Force him into point-blank fights. | Talent: Any

Willow: Pretty big hitbox. Avoid CQB as her attacks and seedling do hella damage. Keep your distance and use air mobility. | Talent: Any

Ying: Without Dimensional Link, she's an easy kill. CQB is key as her range (especially with Focusing Lens) can shut you down pretty fast. Some Ying's use their clones as shields. | Talent: Any

All Tanks: You shouldn't be picking fights with tanks unless they suck or you're coordinating with your team.

Buck: Ensnare and DR Recovery builds.

Grohk: Maelstrom and range.

Grover: Deep roots and range.

Imani: Burst damage, inferno cannon (meme beam), CC, and range.

Jenos: Power Cosmeum, Binary Star + Max Life Rip

Lian: Burst damage and range.

Talus: Overcharge and mobility.

Strix: Super low TTK and invisibility.

Sha Lin: Burst damage, invisibility, and cripple.

Zhin: Possibly the best counter to Andro. Mobility, invincibility, counter, and burst damage.

Evie: Insane mobility and burst.

Pip: Mobility, CC, self-heal.

(Yes I know. "Range" is any flankers biggest counter.)

Vivian: Usually an easy kill but depending on the fight, she can be an absolute nightmare. Analyze her deck and plan your attacks. Baiting out her shield is usually the best option. | Talent: Any

Vora: Usually an easy kill but just like with Vivian, it all depends on the fight. Each of her talents changes her playstyle. Analyze her deck and plan your attacks/counters. | Talent: Any