People with low or telegraphed mobility can get choked by seedlings. Also, anyone with a big hitbox to get Sprouts resets. I'm gonna include most frontlines other than the ones I included because they don't have a shield to block sprouts because all tanks hate dead zone.

Most of my build prioritizes some sort of defense for a reason, she is very susceptible to high burst dive if caught without cooldowns. Fliers, Hitscans, and anything with high mobility or range can easily shut her down if you get too greedy. Characters like Terminus that benefit from spam can be annoying too, so be sure to play carefully with your cooldowns around him.